Padres 2021 Schedule

Believe it or not, the Padres 2021 Schedule has already been announced.

2021 Schedule
The San Diego Padres schedule details for the 2021 baseball season are as follows:

Home Opener

The baseball season returns in 2021 with a home game at Petco Park against the Arizona Diamondbacks on April 1. Fingers crossed. Read more about Padres’ opening day.

Padres Interleague Play

The Padres’ American League opponents for 2021 interleague play will be from the AL West. Home games include the Seattle Mariners, Oakland Athletics, Houston Astros and Los Angeles Angels at Petco Park. Road trips to American League stadiums will take the Padres to face the Texas Rangers Astros, Athletics and Angels.

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The final game of the 2021 regular season will be against the San Francisco Giants on October 3. Want fans to attend those games? Be safe and stop the spread.

And please shop our Padres Store, support the site and gear up with 2021 face masks, shirts, and other fun merchandise!

Petco Park Insider is your guide to enjoying games in San Diego at the Padres baseball stadium. Please join the conversation on Twitter @PetcoParkSD or contact us at Petco Park Insider.

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